Research Review Issue 149, with commentary by A/Prof John Amerena

In this edition:

    • Elevated NT-proBNP as a CV disease risk equivalent
    • Structural cardiac abnormalities in patients with AF/flutter and myocardial injury
    • Subcutaneous vs transvenous ICDs
    • Longer-term all-cause and CV mortality after intensive BP control
    • Management of patients with recurrent traumatic syncope and bifascicular block
    • Single point-of-care hs-cTnI measurement to rule out acute MI
    • Once-weekly tirzepatide for the treatment of obesity
    • DOACs vs VKAs in patients with thrombotic antiphospholipid syndrome
    • Sodium restriction in patients with heart failure
    • Impact of BP reduction in patients with isolated diastolic hypertension

Download this edition here (pdf)

Cardiology Practice Review: Issue 24, with commentary by Dr Janette Tenne

In this edition

  • Myocardial dysfunction after COVID-19 in patients with CV comorbidities
  • ACC/AHA guideline for aortic disease
  • ACC pathway on the evaluation of acute chest pain in the ED
  • USPSTF statement on statin use for CVD prevention
  • Radiation protection in catheterisation laboratories during pregnancy
  • TGA – new indications
  • Use of lipoprotein(a) in clinical practice
  • HCM: imaging to stratify risk of sudden cardiac death
  • COVID-19 resources
  • Conferences, workshops and CPD

Download this Cardiology_Practice_Review_Issue_24 here (pdf)

2024 CSANZ/ANZET-UK structural and interventional Fellowships

Applications are now open for the following 2024 UK structural and interventional fellowships:

ANZET-UK Structural Fellowship at Leeds General Infirmary

ANZET-UK Intervention Fellowship at Leeds General Infirmary

CSANZ-UK Interventional Fellowship at Wythenshawe University Hospital, South Manchester.

Details and eligibility criteria for the ANZET UK Fellowships can be found at this link.

Details and eligibility criteria for the CSANZ UK Fellowships can be found at this link.

To apply, please send a copy of your CV and letters of support from two supervisory consultants to A/Prof Ajay Sinhal at [email protected]

Applications close on Friday, 24 February 2023.   

Heart Failure Research Review: Issue 73, with commentary by Dr Mark Nolan

In this issue:

  • Outpatient intravenous diuretics for worsening HF
    Comparison of HF risk scores for predicting mortality and re-admission
  • Prognosis of transthyretin cardiac amyloidosis without HF symptoms
  • ARNI prescription at hospital discharge in HFREF
  • CV complications of ICIs
  • ASP and HF progression in ARVC
  • Treatment response in recentonset nonischaemic vs. ischaemic HFREF
  • Glycaemic markers and HF subtypes
  • Predicting survival after fully magnetically levitated LVAD implantation

Download the Heart Failure Research Review Issue 73,

Dr Christopher Yu Travelling Fellowship at ESC 2022

Dr Christopher Yu  at ESC 2022

Dr Christopher Yu, Nepean Clinical School, University of Sydney.

I was fortunate to be awarded the 2022 CSANZ ESC Travel Fellowship. This year, the conference was held in Barcelona, Spain and was the first face to face conference in three years due to the COVID-19 pandemic. It was surreal to find my long-lost passport and get back onto a long-haul flight.

I was excited to present part of my PhD at the conference, with two abstracts accepted as moderated poster presentations. The first abstract was a subgroup analysis of the SUCCOUR study assessing the role of baseline left atrial strain in predicting cardiotoxicity. The second abstract was assessing the role of cardiac magnetic resonance relaxometry in detecting anthracycline related changes compared to left ventricular ejection fraction. The presentations were well received, and it was great to receive feedback from the doyens of cardio-oncology. My PhD is under the supervisor of Professor Kazuaki Negishi, Nepean Clinical School, University of Sydney, to whom I am grateful for his supervision and mentorship.

The conference felt particularly special as the first ever cardio-oncology guidelines were launched by Dr Teresa Lopez-Fernandez and Dr Alex Lyon. The main hall was overflowing with attendees, and it was a highlight to feel the buzz and excitement at the largest cardiology conference in the world. It also demonstrated to me that there is so much work to be done in the field to improve the cardiovascular outcomes of our cancer patients. Other highlights included meeting fellow antipodeans and overindulging Catalan food and wine together.

I am extremely grateful to the CSANZ for supporting me to attend this fantastic conference. It has given me inspiration to expand my network and continue my research in cardio-oncology.

View Chris’s presentation here on ESC365

Ada Lo Travelling Fellowship recipient at ESC 2022

Ms Ada Lo at ESC 2022

Ada Lo is the lead sonographer at the Royal Brisbane and Women’s Hospital Cardiology Echo Lab.

I submitted two abstracts of my PhD projects to ESC 2022 and they were accepted as moderated posters.

My job at the Royal Brisbane and Women’s Hospital Cardiology Echo Lab involves training student sonographers and cardiology advanced trainees. I am also heavily involved in research projects and education.

I submitted two abstracts of my PhD project to ESC 2022, and they were accepted as moderated posters: the first moderated poster presented was “Use of advanced echocardiographic modalities to discriminate preclinical HCM mutation carriers from non-carriers”. The second, was entitled “Use of advanced echocardiographic deformation measures to delineate cause of pathological left ventricular hypertrophy: value of a multiparametric approach”.

This was my first time to attend the world class conference, ESC 2022 Congress, and the experience was fantastic. However, I did find that many talks that I attended at the ESC had already been presented in our own CSANZ Annual Scientific Meeting just two weeks prior. I really want to congratulate the organizing committee of our own CSANZ who give us a world class annual meeting.

I was also invited to present in the CSANZ Highlights session on the second day of this conference. It was a great privilege to present together with several experts in Cardiology from Australia. I really enjoyed the interesting case presentations and other moderated abstracts presented from centres around the world. It gave me new insights of how some new measurements can be of use in either research or clinical aspects.

Finally, I want to thank the CSANZ committee for the sponsorship of my trip.

View Ada’s abstracts here on ESC 365.

Dr Julia Isbister Travelling Fellowship for ESC 2022

Dr Julia Isbister at ESC 2022

Dr Julia Isbister, Agnes Ginges Centre for Molecular Cardiology, Centenary Institute and EP fellow at Royal Prince Alfred Hospital, Sydney.

It was a pleasure to travel to the ESC Congress 2022 in Barcelona with the support of a CSANZ Travelling Fellowship for this exciting and energetic meeting.

I am in my final year of my PhD at the Agnes Ginges Centre for Molecular Cardiology, Centenary Institute and EP fellow at Royal Prince Alfred Hospital, Sydney. I was delighted to attend an my first in-person international meeting after the long COVID- enforced hiatus! The chance to meet with existing collaborators in person and hear from leaders in the field, particularly in the area of cardiac genetics and EP, was a wonderful experience.

I presented our recent study looking at concealed cardiomyopathy in autopsy- indeterminate sudden cardiac death victims, participated in the CSANZ daily highlights session showcasing work from Australia and New Zealand and gave an invited talk on the role of genetic testing following sudden cardiac death in the combined CSANZ/ESC session “Sudden cardiac death in the young: All you need to know”.

Many thanks to my PhD supervisors, Chris Semsarian and Ray Sy for their guidance and encouragement, and to the CSANZ for the support to attend and present at ESC 2022!

“Concealed cardiomyopathy” is an important cause of autopsy-inconclusive sudden cardiac death and diagnosis impacts care of surviving relatives https://academic.oup.com/eurheartj/article/43/Supplement_2/ehac544.361/6744468 

 

Khalia Primer AHA 2022 Travelling Fellow Report

Ms Khalia Primer (SA) at AHA 2022

Khalia Primer is a final year University of Adelaide PhD candidate, based at the South Australian Health and Medical Research Institute.

With the support of the Cardiac Society’s Travelling Fellowship, she attended the 2022 AHA Scientific Sessions conference which was held in Chicago from the 5-7 November.

Khalia presented some key findings from her PhD project in the ATVB Elaine W. Raines Early Career Award session, which also included presenters from Canada, the United States, and the United Kingdom.

“It was such a fantastic experience to present my work in this forum. I received a lot of extremely useful feedback from the ATVB Early Career committee who organised the session, and it was wonderful to meet the other presenters as well.

I presented my work on how diabetes affects endothelial cell metabolism, and on a novel gene therapy our lab has created to augment metabolic reprogramming and improve angiogenesis in ischaemic disease.

I’m extremely grateful to my supervisors, Associate Professor Christina Bursill and Dr Joanne Tan for encouraging me to attend the conference, and for all their support throughout my PhD. Thank you also to the Cardiac Society of Australia and New Zealand for their support in assisting me to attend the AHA conference in November.

I’m definitely hoping to go to Adelaide for the ASM next year! I’m moving to Melbourne for medical school but I always love the CSANZ meetings so I’m really hoping to stay involved.”

See Khalia’s abstract:
“Pyruvate Dehydrogenase Kinase 4 is a Novel Regulator of Endothelial Cell Mitochondrial Respiration in Diabetes-Impaired Angiogenesis: Implications for Preventing Diabetic Vascular Complications” in AHA’s Journal, Circulation

https://www.ahajournals.org/doi/10.1161/circ.146.suppl_1.10357

Dr Adeel Khoja – AHA 2022 Travelling Fellowship Report

Dr Adeel Khoja is a PhD Student (Year-3) at Faculty of Health & Medical Sciences, Adelaide Medical School
The University of Adelaide.

As a final year PhD student, it was an amazing experience to attend and present at the American Heart Association (AHA) Scientific Sessions 2022 held from November 04 to 07, 2022 in Chicago, Illinois, USA and that too after almost 3 years.

My moderated digital poster presentation entitled “Pregnancy Complications Are Associated With Premature Coronary Artery Disease – Linking Three South Australian Cohorts” was held on Monday, November 07, 2022 in the Multi-Generational Cardiovascular Risk: Pregnancy and Childhood session. It was an honour to present at the flagship cardiology conference and to receive meaningful feedback and suggestions from some of the great experts in the field. This unique data linkage project merging three South Australian registries forms a major component of my PhD thesis and it was the first time I presented at an international conference as part of my PhD candidature.

In addition, I also got a chance to meet with Prof Salim Virani who works in the area of cardiovascular research at the Baylor College of Medicine (BCM), Houston, Texas. We had a good discussion regarding premature coronary heart disease registry at BCM, Houston exploring ways to compare it with the South Australian registry and later with the South- East Asian registries (including Pakistan and India). We also had some discussion on post-doctoral opportunities in USA particularly at BCM, Houston which he was aware of and highlighted potential opportunities. I also attended some nice poster sessions on epidemiology and public health, rapid-fire presentations on mHealth and community based interventions on achieving lifestyle goals and evidence-based clinical sessions. Overall, it was an amazing experience to be part of such a prestigious cardiology conference.

View Adeel’s abstract here in AHA’s Journal, Circulation

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