2021 Kempson Maddox Lecture presented by Prof Diane Fatkin

The 2021 Kempson Maddox Lecture was presented by Prof Diane Fatkin at the 2021 CSANZ ASM. Prof Fatkin is the  Head of the Sr Bernice Research Program in Inherited Heart Diseases, in the Molecular Cardiology Division of the Victor Chang Cardiac Research Institute.

2021 Kempson Maddox Lecture:   Evolution of the genetics revolution in heart failure management.

View Prof Fatkins’ presentation here – follow link to the CSANZ ASM video on Vimeo.

Prof Diane Fatkin trained in Clinical Cardiology and Molecular Genetics and is currently Head of the Sr Bernice Research Program in Inherited Heart Diseases, in the Molecular Cardiology Division of the Victor Chang Cardiac Research Institute, Sydney. She also holds appointments as Honorary Medical Officer in the Cardiology Department, St Vincent’s Hospital, and Professor (conjoint) in the Faculty of Medicine, UNSW Sydney. Her research is focused on understanding the molecular genetic basis of inherited cardiomyopathies, with a specific interest in familial dilated cardiomyopathy and familial atrial fibrillation. This work spans from clinical and genetics studies in families with inherited cardiomyopathies to functional genomics in the cell, mouse, and zebrafish models. A major objective of the team’s research is the “bench-to-bedside” translation of new insights about disease mechanisms into personalised approaches to patient management.

Sports Cardiology by Dr Belinda Grey and A/Prof Andre Gerche

Dr Belinda Grey
A/Prof Andre La Gerche

Dr Belinda Gray 1,2       A/Prof Andre La Gerche 3,4

  1. Department of Cardiology, Royal Prince Alfred Hospital, Sydney NSW
  2. Central Clinical School, Faculty of Medicine and Health University of Sydney NSW
  3. Baker Heart and Diabetes Institute, Melbourne VIC
  4. St Vincent’s Hospital Melbourne VIC

The emerging sub-specialty of sports cardiology has been an area of significant growth in recent years with recognition that there are unique diagnostic challenges in identifying cardiac pathology and specific management considerations amongst athletes and exercise enthusiasts. Whilst there is an increased general awareness of the importance of physical activity in reducing one’s overall risk of cardiovascular disease there is also increased awareness of the potential for high level athletes to have underlying inherited or acquired cardiovascular disease that may place them at risk of adverse events during physical activity. Therefore the American College of Cardiology and the European Society of Cardiology have established their own councils for Sports Cardiology as well as developing specific sports cardiology guideline documents. There is now a recommendation from both councils, that athletes should be reviewed in a centre with specialised expertise in sports cardiology in order to minimise harm to the athlete; by ensuring diagnostic accuracy and appropriate management recommendations are implemented for sports men and women.

Athletes represent the fittest individuals in our society, yet paradoxically some studies have suggested that they are at increased risk of sudden cardiac death when compared to the general population. Up to 50% of young athlete sudden deaths are due to pre-existing cardiac conditions including inherited heart muscle and heart rhythm problems. Being able to identify those individuals who may be at risk of sudden cardiac death during exercise is only one part of practicing sports cardiology. Being able to accurately order and interpret diagnostic testing in athletes is also a key role of a sports cardiologist. There are a number of “normal” cardiac adaptations that occur in athletes. There are profound changes in cardiac structure, function and electrophysiology. The study of sizeable athletic populations are required to provide an adequate description of the spectrum of normal athletic remodelling. This is critical to enable differentiation from subtle cardiac pathology. Like all areas of cardiology, this is a niche area of knowledge that is required to best manage athletic individuals presenting with syncope, fatigue, palpitations or abnormalities on screening/ incidental findings. Clinicians working in this field will be all too familiar with a simple observation (profound bradycardia, for example) leading to a cascade of tests, an incorrect diagnosis of pathology and exclusion from sport. Or the corollary, such as the athlete with inferolateral T-wave inversion and wall thickness increase that is diagnostic of hypertrophic cardiomyopathy but is incorrectly labelled ‘athlete’s heart’ because of vague recall that athletes have funny ECGs and echos.

The practice of sports cardiology requires a knowledge of cardiac imaging, clinical electrophysiology and inherited heart disease superimposed with an appreciation of exercise physiology. Moreover, like all fields of cardiology, expertise is acquired through practice and observation. There are established dedicated sports cardiology courses and training programs in Europe and the United States. As a rapidly evolving field, we are interested to assess what the demand might be for a structured program in Australasia.

We have developed dedicated specialised sports cardiology services in Sydney and Melbourne and are aware of several specialists around Australia and New Zealand who have a dedicated interest and expertise. We believe that it is timely to form an interest group within CSANZ to assess demand for training and dedicated service provision whilst also providing a forum for discussing interesting cases and progress within this niche field. We invite any interested parties to contact us as we seek to establish the CSANZ working group for sports cardiology.

Prof Nicholls says “We CAN stabilise plaques after an ACS”

We were excited to see a lot of CSANZ presenters at this year’s ESC Cardiology Conference held over the past 3 days 27 – 30 August 2021. Also featured – in the Late Breaking Trials was Monash University and Victorian Heart Institute’s Director, (and CSANZ President elect) Prof Stephen Nicholls presenting the novel findings of the HUYGENS Study.
This research shows that treatment with high dose statins and Evolocumab stabilises vulnerable plaque in one year.

Prof Nicholls says “We CAN stabilise plaques after an ACS”

Prof Chris Semsarian presented at the ESC Congress Digital 2021

Prof Chris Semsarian presented at the 2021 ESC Congress last weekend.  Chris was part of the panel, Meet the Experts: sudden cardiac death in the patient with an apparent normal heart.  His presentation was very well received and discussed, it was a multi approach to arrive to a correct diagnosis of Sudden Cardiac Death in the patient with an apparently normal heart.

 

 

The 2021 R T Hall Prize winners are Professor Peter Thompson and Professor Mark Nidorf 

Congratulations to the 2021 R T Hall Prize Winners: Professor Peter Thompson and Professor Mark Nidorf 

Professors Thompson and Nidorf have made a significant contribution to cardiovascular medicine in their pursuit of the role of colchicine in preventing coronary events.

In the last 14 years Nidorf and Thompson’s work has propelled the idea of treating atherosclerotic inflammation with colchicine from the bedside into the international spotlight. Not only has it helped to “close the loop” on the inflammatory hypothesis of atherosclerosis, but colchicine’s potential as a cornerstone therapy for secondary prevention coronary disease with an inexpensive readily available drug with an impressive safety profile, is now seriously considered. Work continues to determine if early intolerance to colchicine can be reduced by differing dosing regimens and how best to monitor anti-inflammatory effect in atherosclerosis. The evidence from trials completed to date suggest that repurposing colchicine for secondary prevention of CV disease has the potential to change practice and have a global impact on CV disease. 

Congratulations to Prof Clara Chow and her Quartet team!

Congratulations to Prof Clara Chow and her Quartet Investigators team.

Exciting to see Prof Chow share and present the results of the QUARTET at the 2021 Digital ESC Congress over the weekend and simultaneously released by The Lancet.see link below

Prof Chow said that she was so excited to have delivered it, “…several ups and downs [along the] way.. would love to see it shake it up on how we do things in managing High BP”.

Please feel free to ask Clara Chow any questions via the Discussion Forum on this page.

 

authors.elsevier.com – READ in full on The Lancet here

Congratulations to the CSANZ 2021 Prizewinners

ALLIED HEALTH SCIENCE, TECHNOLOGY PRIZE

Ingrid Stacey, University of WA

Abstract:  Long-term outcomes after RHD diagnosis in Australia: a linked data study.

Judges: Leah Wright, Stephanie Partridge

CARDIOVASCULAR GENETICS PRIZE

Stacey Peters, Royal Melbourne Hospital, VIC

Abstract: Arrhythmias are a Requisite Feature of SCN5A Mediated Dilated Cardiomyopathy : A Systematic Review of Variants

Judges: Jon Skinner, Kathryn Waddell-Smith

CARDIAC IMAGING PRIZE

Siddharth Trivedi, Westmead Hospital, NSW

Speckle tracking echocardiography predicts arrhythmia recurrence in patients with structural heart disease following ventricular tachycardia ablation.

Judges: Sudhir Wahi, Angeline Leet

CARDIOVASCULAR NURSING PRIZE

Lynda Tivendale, Royal Melbourne Hospital, VIC

Multimodal lung and sternal ultrasound education program for cardiothoracic nurses and physiotherapists.

Judges: Robyn Clarke, Jan Cameron, Judith Finn

HEART FAILURE PRIZE

Praveen Indraratna, Prince of Wales Hospital, NSW

TeleClinical Care: A randomised control trial of a smartphone-based model of care for patients with heart failure or acute coronary syndrome.

Judges: Mayanna Lund, Aaron Sverdlov

HEART RHYTHM PRIZE

Varun Malik, Royal Adelaide Hospital, SA

AF begets autonomic nervous system dysfunction: a possible contributor to “AF begets AF”.

Judges: Saurabh Kumar, Martin Stiles

INDIGENEOUS HEALTH PRIZE

Katharine McBride, SAHMRI, SA

When the heart is spiritually and physically strong, women have lower incident cardiovascular disease: Quantifying Aboriginal women’s narrative of cardiovascular protection.

Judges: Judith Katzenellenbogen, William Wang

PAEDIATRIC AND CONGENITAL CARDIOLOGY PRIZE

Karina Laohachai, Women’s and Children’s Hospital, SA

Older age of Fontan completion is associated with impaired lung function.

Judges: Michael Cheung, Mugur Nicolae

PREVENTATIVE CARDIOLOGY PRIZE

Kasun De Silva, Westmead Hospital, NSW

Sex-based differences in implantation of pacemakers, implantable cardioverter defibrillators and cardiac resynchronisation therapy: a 10-year study of 1,291,258 patients in New South Wales.

Judges: Stephen Nicholls, David Colquhoun

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